兔抗JAK2(Ab-570) 多克隆抗體

Background:

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Applications:

WB, IF

Name of antibody:

JAK2(Ab-570)

Immunogen:

Synthesized non-phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 570 (G-D-Y(p)-G-Q).

Full name:

Janus kinase 2

Synonyms：

JTK10; THCYT3

SwissProt:

O60674

WB Predicted band size:

131 kDa

WB Positive control:

293 cells treated with etoposide (25uM, 24hours) lysate

WB Recommended dilution:

500-3000

IF positive control:

NIH/3T3 cells

IF Recommend dilution:

100-500