中文名稱: 兔抗ADD1多克隆抗體
Background: |
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. |
Applications: |
ELISA, IHC |
Name of antibody: |
ADD1 |
Immunogen: |
Fusion protein of human ADD1 |
Full name: |
Alpha-adducin |
Synonyms: |
ADDA |
SwissProt: |
P35611 |
ELISA Recommended dilution: |
500-5000 |
IHC positive control: |
Human lung cancer |
IHC Recommend dilution: |
50-200 |