Background:
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.
Applications:
ELISA, WB, IHC
Name of antibody:
KDM5A
Immunogen:
Synthetic peptide of human KDM5A
Full name:
lysine (K)-specific demethylase 5A
Synonyms:
RBP2; RBBP2; RBBP-2
SwissProt:
P29375
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human liver cancer and Human esophagus cancer
IHC Recommend dilution:
50-300
WB Predicted band size:
192 kDa
WB Positive control:
231 and hela cells
WB Recommended dilution:
500-2000
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