技術(shù)規(guī)格
Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined.
Applications:
ELISA, IHC
Name of antibody:
KLK4
Immunogen:
Fusion protein of human KLK4
Full name:
kallikrein-related peptidase 4
Synonyms:
ARM1; EMSP; PSTS; AI2A1; EMSP1; KLK-L1; PRSS17; kallikrein
SwissProt:
Q9Y5K2
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human cervical cancer and human thyroid cancer
IHC Recommend dilution:
25-100