兔抗LAT2多克隆抗體

Background:

This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

Applications:

ELISA, IHC

Name of antibody:

LAT2

Immunogen:

Fusion protein of human LAT2

Full name:

linker for activation of T cells family, member 2

Synonyms：

LAB, NTAL, WSCR5, WBSCR5, HSPC046, WBSCR15

SwissProt:

Q9GZY6

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer

IHC Recommend dilution:

10-50