兔抗LMTK2多克隆抗體

Background:

The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis.

Applications:

WB, IHC, IF

Name of antibody:

LMTK2

Immunogen:

Synthesized peptide derived from internal of human LMTK2.

Full name:

lemur tyrosine kinase 2

Synonyms：

BREK; KPI2; LMR2; cprk; KPI-2; AATYK2; PPP1R100

SwissProt:

Q8IWU2

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

165 kDa

WB Positive control:

LOVO cells lysate

WB Recommended dilution:

500-3000

IF positive control:

HepG2 cells

IF Recommend dilution:

100-500