Background: |
Leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3) was identified by microarray analysis among genes that show differential expression during gastrulation in Xenopus laevis. Lrig3 was expressed in the neural plate and neural crest (NC) at neurula stages, and in NC derivatives and other dorsal structures during tailbud stages. A prominent consequence of the morpholino-induced inhibition of Lrig3 expression was impaired NC formation, as revealed by the suppression of marker genes, including Slug, Sox9 and Foxd3. |
Applications: |
ELISA, IHC |
Name of antibody: |
LRIG3 |
Immunogen: |
Synthetic peptide of human LRIG3 |
Full name: |
leucine-rich repeats and immunoglobulin-like domains 3 |
Synonyms: |
LIG3 |
SwissProt: |
Q6UXM1 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human esophagus cancer |
IHC Recommend dilution: |
25-100 |