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  • HBG1/HBG2 抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW11517
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：75
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中文名稱(chēng)：HBG1/HBG2 抗原（重組蛋白）

英文名稱(chēng)：HBG1/HBG2 Antigen (Recombinant Protein)

別      名：hemoglobin subunit gamma 1/2; fetal hemoglobin; HBGA; HBGR; HBG-T2; HSGGL1; PRO2979; TNCY; HBG-T1

儲(chǔ)      存：冷凍（-20℃）

相關(guān)類(lèi)別：抗原

概述

Fusion protein corresponding to a region derived from 2-121 amino acids of human HBG1/HBG2


技術(shù)規(guī)格

Full name:

hemoglobin subunit gamma 1/2

Synonyms:

fetal hemoglobin; HBGA; HBGR; HBG-T2; HSGGL1; PRO2979; TNCY; HBG-T1

Swissprot:

P69891/P69892

Gene Accession:

BC010914

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.