購(gòu)物車(chē)
幫助
021-54845833/15800441009
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Background: |
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
WB, IHC |
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Name of antibody: |
RASSF8 |
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Immunogen: |
Fusion protein of human RASSF8 |
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Full name: |
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 (RASSF8), transcript variant 4 |
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Synonyms: |
C12orf2; HOJ1 |
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SwissProt: |
Q8NHQ8 |
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IHC positive control: |
adenocarcinoma of human ovary tissue |
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IHC Recommend dilution: |
100-500 |
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WB Predicted band size: |
48 kDa |
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WB Positive control: |
HepG2, Hela, COS7, MDCK, MCF-7 cell lysates |
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WB Recommended dilution: |
500-2000 |
