小鼠抗RBPJ單克隆抗體

Background:

The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.

Applications:

WB

Name of antibody:

RBPJ

Immunogen:

Fusion protein of human RBPJ

Full name:

recombination signal binding protein for immunoglobulin kappa J region

Synonyms:

SUH; csl; AOS3; CBF1; KBF2; RBP-J; RBPJK; IGKJRB; RBPSUH; IGKJRB1

SwissProt:

Q06330

WB Predicted band size:

56 KD

WB Positive control:

293T, K562, HepG2, Hela, MCF7 cell lysates

WB Recommended dilution:

200-1000