購(gòu)物車(chē)
幫助
021-54845833/15800441009
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Background: |
Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
GANAB |
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Immunogen: |
Synthetic peptide of human GANAB |
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Full name: |
anaphase promoting complex subunit 11 |
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Synonyms： |
APC11; Apc11p; HSPC214 |
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SwissProt: |
Q14697 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human gastric cancer and human lung cancer |
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IHC Recommend dilution: |
25-100 |
