小鼠抗SIRPB1單克隆抗體

Background:

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

SIRPB1

Immunogen:

Fusion protein of human SIRPB1

Full name:

signal regulatory protein beta 1

Synonyms:

CD172b; SIRP-BETA-1

SwissProt:

O00241

WB Predicted band size:

43 KD

WB Positive control:

A549, COS7, MDCK cell lysates

WB Recommended dilution:

200-1000