技術(shù)規(guī)格
Background: |
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. |
Applications: |
WB |
Name of antibody: |
PPP2R1B |
Immunogen: |
Fusion protein of human PPP2R1B |
Full name: |
protein phosphatase 2 scaffold subunit Abeta |
Synonyms: |
PR65B; PP2A-Abeta |
SwissProt: |
P30154 |
WB Predicted band size: |
66 KD |
WB Positive control: |
Jurkat, HEK293, Hela cell lysates |
WB Recommended dilution: |
500-2000 |