兔抗AIRE(Phospho-Ser156) 多克隆抗體

Background:

This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]

Applications:

WB

Name of antibody:

AIRE(Phospho-Ser156)

Immunogen:

Peptide sequence around phosphorylation site of Serine156 P-G-S(p)-Q-L) derived from Human AIRE.

Full name:

autoimmune regulator

Synonyms：

APS1; APSI; PGA1; AIRE1; APECED

SwissProt:

O43918

WB Predicted band size:

58 kDa

WB Positive control:

Hela cells lysates treated with Hu

WB Recommended dilution:

500-1000