中文名稱:兔抗COL9A1多克隆抗體
Background: |
This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
COL9A1 |
Immunogen: |
Fusion protein of human COL9A1 |
Full name: |
collagen type IX alpha 1 chain |
Synonyms: |
MED; EDM6; STL4; DJ149L1.1.2 |
SwissProt: |
P20849 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |