中文名稱:ALG12 抗原(重組蛋白)
英文名稱: ALG12 Antigen (Recombinant Protein)
別 名: ALG12, alpha-1,6-mannosyltransferase; CDG1G; ECM39; hALG12; PP14673
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 367-488 amino acids of human ALG12 |
Full name: |
ALG12, alpha-1,6-mannosyltransferase |
Synonyms: |
CDG1G; ECM39; hALG12; PP14673 |
Swissprot: |
Q9BV10 |
Gene Accession: |
BC001729 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. |