概 述
技術(shù)規(guī)格
Full name: |
Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
Synonyms: |
LYS2; LYS5; CGI-80; AASD-PPT |
Swissprot: |
Q9NRN7 |
Gene Accession: |
BC015470 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. |