Background: |
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
CTSL |
Immunogen: |
Fusion protein of human CTSL |
Full name: |
cathepsin L |
Synonyms: |
MEP; CATL; CTSL1 |
SwissProt: |
P07711 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human brain and Human thyroid cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
38 kDa |
WB Positive control: |
Mouse kidney tissue and A172 cells |
WB Recommended dilution: |
500-2000 |