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  • CHMP2B 抗原(重組蛋白

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16321
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:60
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中文名稱: CHMP2B 抗原(重組蛋白)

英文名稱: CHMP2B Antigen (Recombinant Protein)

別     名: charged multivesicular body protein 2B; DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5

儲     存: 冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 94-213 amino acids of human CHMP2B

技術(shù)規(guī)格

Full name:

charged multivesicular body protein 2B

Synonyms:

DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5

Swissprot:

Q9UQN3

Gene Accession:

BC001553

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.