CHCHD3抗原（重組蛋白）

Full name:

coiled-coil-helix-coiled-coil-helix domain containing 3

Synonyms:

Mic19; MINOS3; PPP1R22

Swissprot:

Q9NX63

Gene Accession:

BC011596

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS). Several transcript variants encoding different isoforms have been found for this gene.