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  • EIF2AK3抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16718
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:40
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中文名稱: EIF2AK3抗原(重組蛋白)

英文名稱: EIF2AK3 Antigen (Recombinant Protein)

別       名: PEK; WRS; PERK

儲(chǔ)       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 867-1116 amino acids of human EIF2AK3

技術(shù)規(guī)格

Full name:

eukaryotic translation initiation factor 2 alpha kinase 3

Synonyms:

PEK; WRS; PERK

Swissprot:

Q9NZJ5

Gene Accession:

BC126354

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.