LF11抗原（重組蛋白）

Full name:

Kruppel-like factor 11

Synonyms:

FKLF; FKLF1; MODY7; TIEG2; Tieg3

Swissprot:

O14901

Gene Accession:

BC063286

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.