中文名稱(chēng):ATG4D抗原(重組蛋白)
英文名稱(chēng): ATG4D Antigen (Recombinant Protein)
別 名: APG4D; AUTL4; APG4-D
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概 述:
Fusion protein corresponding to a region derived from 334-474 amino acids of human ATG4D |
Full name: |
autophagy related 4D, cysteine peptidase |
Synonyms: |
APG4D; AUTL4; APG4-D |
Swissprot: |
Q86TL0 |
Gene Accession: |
BC007639 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. |