中文名稱:ATP2C1抗原(重組蛋白)
英文名稱: ATP2C1 Antigen (Recombinant Protein)
別 名: HHD; BCPM; PMR1; SPCA1; hSPCA1; ATP2C1A
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 380-650 amino acids of human ATP2C1 |
Full name: |
ATPase, Ca++ transporting, type 2C, member 1 |
Synonyms: |
HHD; BCPM; PMR1; SPCA1; hSPCA1; ATP2C1A |
Swissprot: |
P98194 |
Gene Accession: |
BC028139 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. |