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  • MPZ抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16862
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:40
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中文名稱: MPZ抗原(重組蛋白)

英文名稱: MPZ Antigen (Recombinant Protein)

別      名: P0; CHM; DSS; MPP; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; HMSNIB

儲       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 1-248 amino acids of human MPZ

技術(shù)規(guī)格

Full name:

myelin protein zero

Synonyms:

P0; CHM; DSS; MPP; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; HMSNIB

Swissprot:

P25189

Gene Accession:

BC006491

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. The P0 glycoprotein, absent in the central nervous system,[1] is a major component of the myelin sheath in peripheral nerves. It comprises a large extracellular N-terminal domain, a single transmembrane (TM) region, and a smaller positively charged intracellular domain.