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  • MSH4抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16867
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：40
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中文名稱(chēng)： MSH4抗原（重組蛋白）

英文名稱(chēng)： MSH4 Antigen (Recombinant Protein)

儲(chǔ)       存： 冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概述

Fusion protein corresponding to a region derived from C terminal 300 amino acids of human MSH4

技術(shù)規(guī)格

Full name:

mutS homolog 4

Swissprot:

O15457

Gene Accession:

BC033030

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.