中文名稱: CARD11抗原(重組蛋白)
英文名稱: CARD11 Antigen (Recombinant Protein)
別 名: PPBL; BENTA; BIMP3; IMD11; CARMA1
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 300-502 amino acids of human CARD11 |
Full name: |
caspase recruitment domain family, member 11 |
Synonyms: |
PPBL; BENTA; BIMP3; IMD11; CARMA1 |
Swissprot: |
Q9BXL7 |
Gene Accession: |
BC111719 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. |