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  • PEG10抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17034
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:40
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中文名稱: PEG10抗原(重組蛋白)

英文名稱: PEG10 Antigen (Recombinant Protein)

別       名: EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3

儲       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to C terminal 250 amino acids of human PEG10

技術(shù)規(guī)格

Full name:

paternally expressed 10

Synonyms:

EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3

Swissprot:

Q86TG7

Gene Accession:

BC050659

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.