購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
DCTN3 |
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Immunogen: |
Fusion protein of human DCTN3 |
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Full name: |
dynactin 3 (p22) |
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Synonyms： |
DCTN22; DCTN-22 |
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SwissProt: |
O75935 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human thyroid cancer and human cervical cancer |
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IHC Recommend dilution: |
100-300 |
