歡迎來(lái)到上海通蔚！

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當(dāng)前位置: 首頁(yè) > 科研產(chǎn)品 > 科研抗體 > 其他抗體 > MRE11抗原（重組蛋白）

產(chǎn)品中心

  • MRE11抗原（重組蛋白）

    規(guī)格：
    數(shù)量：

    購(gòu)買數(shù)量

    價(jià)格：￥
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17451
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：40
  • 商品詳情
  • 參考文獻(xiàn)
  • 說明書下載
  • 商品評(píng)論0
  • 相關(guān)產(chǎn)品
中文名稱： MRE11抗原（重組蛋白）

英文名稱： MRE11 Antigen (Recombinant Protein)

別      名： MRE11 homolog, double strand break repair nuclease; ATLD; HNGS1; MRE11A; MRE11B

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to N terminal 180 amino acids of human MRE11

技術(shù)規(guī)格

Full name:

MRE11 homolog, double strand break repair nuclease

Synonyms:

ATLD; HNGS1; MRE11A; MRE11B

Swissprot:

P49959

Gene Accession:

NP_005582

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.