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  • PIM2抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17548
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱:PIM2抗原(重組蛋白)

英文名稱: PIM2 Antigen (Recombinant Protein)

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別 抗原

概  述:

Fusion protein corresponding to a region derived from 35-286 amino acids of human PIM2


技術(shù)規(guī)格:

Full name:

pim-2 oncogene

Swissprot:

Q9P1W9

Gene Accession:

BC018111

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.