中文名稱(chēng): SLAMF1抗原(重組蛋白)
英文名稱(chēng): SLAMF1 Antigen (Recombinant Protein)
別 名: SLAM; CD150; CDw150
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概 述:
Fusion protein corresponding to N terminal 124 amino acids of human SLAMF1 |
Full name: |
signaling lymphocytic activation molecule family member 1 |
Synonyms: |
SLAM; CD150; CDw150 |
Swissprot: |
Q13291 |
Gene Accession: |
BC067847 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. |