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  • SPTLC1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17687
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱SPTLC1抗原(重組蛋白)

英文名稱: SPTLC1 Antigen (Recombinant Protein)

別      名: HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to C terminal 250 amino acids of human SPTLC1


技術(shù)規(guī)格:

Full name:

serine palmitoyltransferase, long chain base subunit 1

Synonyms:

HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1

Swissprot:

O15269

Gene Accession:

BC068537

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.