兔抗ALPP多克隆抗體

Background:

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Applications:

ELISA, WB, IHC

Name of antibody:

ALPP

Immunogen:

Fusion protein of human ALPP

Full name:

alkaline phosphatase, placental

Synonyms：

ALP; PALP; PLAP; PLAP-1

SwissProt:

P05187

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human lung cancer and Human thyroid cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

58 kDa

WB Positive control:

HepG2 cells and human placenta tissue

WB Recommended dilution:

1000-5000