YARS2抗原（重組蛋白）

Full name:

tyrosyl-tRNA synthetase 2, mitochondrial

Synonyms:

TYRRS; CGI-04; MLASA2; MT-TYRRS

Swissprot:

Q9Y2Z4

Gene Accession:

BC015625

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).