NUMB抗原（重組蛋白）

Full name:

NUMB endocytic adaptor protein

Synonyms:

S171; C14orf41; c14_5527

Swissprot:

P49757

Gene Accession:

BC020788

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.