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  • PDCD1抗原

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    • 品牌 : 通蔚生物
    • 目錄號 : TW18001
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱: PDCD1抗原 

英文名稱: PDCD1 Antigen

相關(guān)類別: 抗原

儲    存 冷凍(-20℃) 

概述

Synthetic peptide corresponding to a region derived from 270-284 amino acids of human Programmed cell death 1

技術(shù)規(guī)格

Full name

Programmed cell death 1

Synonyms

PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l

Swissprot

Q15116

Gene Accession

NP_005009

Background

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.