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  • PGRMC2抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW18063
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：40
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中文名稱：  PGRMC2抗原（重組蛋白）

英文名稱： PGRMC2 Antigen (Recombinant Protein)

別       名： progesterone receptor membrane component 2; DG6; PMBP

儲       存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 101-223 amino acids of human PGRMC2

技術(shù)規(guī)格

Full name:

progesterone receptor membrane component 2

Synonyms:

DG6; PMBP

Swissprot:

O15173

Gene Accession:

BC016692

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.