中文名稱(chēng): 兔抗MCM6多克隆抗體
英文名稱(chēng): Anti-MCM6 rabbit polyclonal antibody
別 名: Mis5; P105MCM; MCG40308
抗 原: MCM6
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
相關(guān)類(lèi)別: 一抗
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類(lèi)型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
MCM6 |
Immunogen: |
Fusion protein of human MCM6 |
Full name: |
minichromosome maintenance complex component 6 |
Synonyms: |
Mis5; P105MCM; MCG40308 |
SwissProt: |
Q14566 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human cervical cancer and human tonsil |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
93 kDa |
WB Positive control: |
293T, K562, NIH/3T3 and hela cells |
WB Recommended dilution: |
500-2000 |