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  • MYOT抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18299
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱:MYOT抗原(重組蛋白)

英文名稱: MYOT Antigen (Recombinant Protein)

別      名: MFM3; TTID; TTOD; LGMD1; LGMD1A

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別 抗原

概      述:

Fusion protein corresponding to a region derived from 299-498 amino acids of human MYOT


技術(shù)規(guī)格:

Full name:

myotilin

Synonyms:

MFM3; TTID; TTOD; LGMD1; LGMD1A

Swissprot:

Q9UBF9

Gene Accession:

BC005376

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.