中文名稱:PHF5A抗原(重組蛋白)
英文名稱: PHF5A Antigen (Recombinant Protein)
別 名: INI; Rds3; SF3B7; SAP14b; SF3b14b; bK223H9.2
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 1-110 amino acids of human PHF5A |
Full name: |
PHD finger protein 5A |
Synonyms: |
INI; Rds3; SF3B7; SAP14b; SF3b14b; bK223H9.2 |
Swissprot: |
Q7RTV0 |
Gene Accession: |
BC007321 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes. |