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  • RIC8A抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18396
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：90
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中文名稱：RIC8A抗原（重組蛋白）

英文名稱： RIC8A Antigen (Recombinant Protein)

別      名： RIC8

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概      述：

Fusion protein corresponding to a region derived from 332-531 amino acids of human RIC8A


技術(shù)規(guī)格：

Full name:

RIC8 guanine nucleotide exchange factor A

Synonyms:

RIC8

Swissprot:

Q9NPQ8

Gene Accession:

BC011821

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.