兔抗ANAPC15多克隆抗體

Background:

ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.

Applications:

ELISA, IHC

Name of antibody:

ANAPC15

Immunogen:

Synthetic peptide of human ANAPC15

Full name:

anaphase promoting complex subunit 15

Synonyms:

APC15; HSPC020; C11orf51

SwissProt:

P60006

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer and human gastric cancer

IHC Recommend dilution:

40-200