購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗MMP14多克隆抗體
英文名稱： Anti-MMP14 rabbit polyclonal antibody
別 名： MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1
抗 原： MMP14
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
相關(guān)類別： 一抗
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MMP14 |
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Immunogen: |
Fusion protein of human MMP14 |
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Full name: |
matrix metallopeptidase 14 (membrane-inserted) |
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Synonyms： |
MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1 |
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SwissProt: |
P50281 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
