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  • HSPB8抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW19271
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：60
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中文名稱： HSPB8抗原（重組蛋白）

英文名稱： HSPB8 Antigen (Recombinant Protein)

別     名：  H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

heat shock 22kDa protein 8

Synonyms:

H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22

Swissprot:

Q9UJY1

Gene Accession:

BC002673

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.