別 名: HAT4; NAT15
儲(chǔ) 存: 冷凍(-20℃)
Full name: |
N(alpha)-acetyltransferase 60, NatF catalytic subunit |
Synonyms: |
HAT4; NAT15 |
Swissprot: |
Q9H7X0 |
Gene Accession: |
BC011267 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Histone acetyltransferase localized in the Golgi apparatus that mediates acetylation of free histone H4, thereby facilitating nucleosome assembly. Has a preference for free histone H4 'Lys-20'(H4K20ac), 'Lys-79'(H4K79ac) and 'Lys-91' (H4K91ac). Also displays alpha (N-terminal) acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. |