兔抗EMC10多克隆抗體

Background:

EMC10, also known as C19orf63, C19orf63 is a 262 amino acid protein that exists as two alternatively isoforms and are encoded by a gene located on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.

Applications:

ELISA, WB, IHC

Name of antibody:

EMC10

Immunogen:

Synthetic peptide of human EMC10

Full name:

ER membrane protein complex subunit 10

Synonyms:

HSM1; HSS1; C19orf63

SwissProt:

Q5UCC4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and human lung cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

27 kDa

WB Positive control:

Jurkat,PC-3 and A549 cell lysates

WB Recommended dilution:

200-1000