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  • POR 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW19547
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:60
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中文名稱: POR 抗原(重組蛋白)

英文名稱: POR Antigen (Recombinant Protein)

別     名:  cytochrome p450 oxidoreductase; CPR; CYPOR; P450R

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 478-677 amino acids of human POR

技術(shù)規(guī)格

Full name:

cytochrome p450 oxidoreductase

Synonyms:

CPR; CYPOR; P450R

Swissprot:

P16435

Gene Accession:

BC034277

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.