兔抗UBE2V1多克隆抗體

Background:

Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Applications:

ELISA, WB, IHC

Name of antibody:

UBE2V1

Immunogen:

Full length fusion protein

Full name:

ubiquitin conjugating enzyme E2 variant 1

Synonyms:

CIR1; UEV1; CROC1; UBE2V; UEV-1; UEV1A; CROC-1

SwissProt:

Q13404

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and human breast cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

16 kDa

WB Positive control:

Human fetal brain tissue,HT-29 cell and Jurkat cell lysates

WB Recommended dilution:

500-2000