兔抗RAPSN多克隆抗體

Background:

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

ELISA, IHC

Name of antibody:

RAPSN

Immunogen:

Fusion protein of human RAPSN

Full name:

receptor associated protein of the synapse

Synonyms:

FADS; CMS11; CMS4C; RAPSYN; RNF205

SwissProt:

Q13702

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-50